陳慎寶; 丁如寧
南京醫(yī)科大學(xué)微生物學(xué)教研室!南京210029; 南京醫(yī)科大學(xué)微生物學(xué)教研室!南京210029

【中文摘要】 中國(guó)古代著名藥用菌槐耳（Trametes robinpphila Murr.）在營(yíng)養(yǎng)基質(zhì)上進(jìn)行固體發(fā)酵,產(chǎn)生槐耳菌質(zhì),從中提取的清膏及進(jìn)一步提取的蛋白多糖,都有顯著的抑制動(dòng)物體內(nèi)瘤和延長(zhǎng)生命等作用,抑癌率可達(dá)50％左右.清膏治療中晚期原發(fā)性肝癌總有效率達(dá)75.71％,它們具有促進(jìn)多種免疫功能的作用,是良好的生物反應(yīng)調(diào)節(jié)劑（BRM）,并有可能進(jìn)一步擴(kuò)大其適應(yīng)癥.

【英文摘要】 Through solid fermentation in nutrient substratum, Trametes robiniophila Murr. (TRM), used as a famous medicinal fungi in ancient china, produced fungal substance from which clear paste and further isolated proteoglycan had been extracted. Both clear paste and proteo'glycan had tumor-inhibition effect on experimental animals and prolonged the life of infected animals And the tumor inhibition rate ia about 50%. Patients with middle or later period primary hepatoma treated with the paste, had got a total efficient rate of about 75%. Both the TRM clear paste and the proteoglycan promoted various immune functions. They are good biological response modifier and may be used to treat other adaptive diseases.

【中文關(guān)鍵詞】 槐耳; 菌質(zhì); 清膏; 生物反應(yīng)調(diào)節(jié)劑
【英文關(guān)鍵詞】 Trametes robiniophila Murr.; Fungal substance; Clear paste; Biological response modifier

【文獻(xiàn)出處】 食用菌學(xué)報(bào),Acta Edulis Fungi,編輯部郵箱,1995年01期 【DOI】CNKI:SUN:SYJB.0.1995-01-004